diff --git a/ports/libpng/fix-export-targets.patch b/ports/libpng/fix-export-targets.patch
index bea2daaf5a..1cf66784bc 100644
--- a/ports/libpng/fix-export-targets.patch
+++ b/ports/libpng/fix-export-targets.patch
@@ -1,10 +1,10 @@
 diff --git a/CMakeLists.txt b/CMakeLists.txt
-index e355e4d..3e2f346 100644
+index eaba327..dbd31d7 100644
 --- a/CMakeLists.txt
 +++ b/CMakeLists.txt
-@@ -1053,6 +1053,12 @@ if(NOT SKIP_INSTALL_EXPORT AND NOT SKIP_INSTALL_ALL)
+@@ -1126,6 +1126,12 @@ if(NOT SKIP_INSTALL_EXPORT AND NOT SKIP_INSTALL_ALL)
    install(EXPORT libpng
-           DESTINATION lib/libpng
+           DESTINATION ${CMAKE_INSTALL_LIBDIR}/libpng
            FILE libpng${PNGLIB_ABI_VERSION}.cmake)
 +  file(WRITE "${CMAKE_CURRENT_BINARY_DIR}/libpng-config.cmake" "
 +  include(CMakeFindDependencyMacro)
diff --git a/ports/libpng/fix-msa-support-for-mips.patch b/ports/libpng/fix-msa-support-for-mips.patch
index 163586a5d0..648de85d81 100644
--- a/ports/libpng/fix-msa-support-for-mips.patch
+++ b/ports/libpng/fix-msa-support-for-mips.patch
@@ -1,11 +1,11 @@
 diff --git a/CMakeLists.txt b/CMakeLists.txt
-index e355e4d..990e32a 100644
+index 3857b82..4c68989 100644
 --- a/CMakeLists.txt
 +++ b/CMakeLists.txt
-@@ -188,8 +188,8 @@ endif()
+@@ -221,8 +221,8 @@ endif()
+ 
  # Set definitions and sources for MIPS.
- if(TARGET_ARCH MATCHES "mipsel*" OR
-    TARGET_ARCH MATCHES "mips64el*")
+ if(TARGET_ARCH MATCHES "^(mipsel|mips64el)")
 -  set(PNG_MIPS_MSA_POSSIBLE_VALUES on off)
 -  set(PNG_MIPS_MSA "on"
 +  set(PNG_MIPS_MSA_POSSIBLE_VALUES on off check)
@@ -13,12 +13,16 @@ index e355e4d..990e32a 100644
        CACHE STRING "Enable MIPS_MSA optimizations: on|off; on is default")
    set_property(CACHE PNG_MIPS_MSA
                 PROPERTY STRINGS ${PNG_MIPS_MSA_POSSIBLE_VALUES})
-@@ -202,6 +202,8 @@ if(TARGET_ARCH MATCHES "mipsel*" OR
+@@ -254,6 +254,12 @@ if(TARGET_ARCH MATCHES "^(mipsel|mips64el)")
          mips/filter_msa_intrinsics.c)
-     if(${PNG_MIPS_MSA} STREQUAL "on")
-       add_definitions(-DPNG_MIPS_MSA_OPT=2)
-+    else()
-+      add_definitions(-DPNG_MIPS_MSA_CHECK_SUPPORTED)
-     endif()
-   else()
-     add_definitions(-DPNG_MIPS_MSA_OPT=0)
+     add_definitions(-DPNG_MIPS_MSA_OPT=2)
+     add_definitions(-DPNG_MIPS_MMI_OPT=0)
++  elseif(PNG_MIPS_MSA STREQUAL "check")
++    set(libpng_mips_sources
++        mips/mips_init.c
++        mips/filter_msa_intrinsics.c)
++    add_definitions(-DPNG_MIPS_MSA_CHECK_SUPPORTED)
++    add_definitions(-DPNG_MIPS_MMI_CHECK_SUPPORTED)
+   elseif(PNG_MIPS_MMI STREQUAL "on")
+     set(libpng_mips_sources
+         mips/mips_init.c
diff --git a/ports/libpng/libm.patch b/ports/libpng/libm.patch
index a60e65cd1c..6960021905 100644
--- a/ports/libpng/libm.patch
+++ b/ports/libpng/libm.patch
@@ -1,17 +1,17 @@
 diff --git a/CMakeLists.txt b/CMakeLists.txt
-index 958b1d6..21c8941 100644
+index dbd31d7..7deb6c2 100644
 --- a/CMakeLists.txt
 +++ b/CMakeLists.txt
-@@ -84,6 +84,12 @@ endif()
+@@ -109,6 +109,12 @@ elseif(POLICY CMP0074)
+ endif()
  
  if(UNIX AND NOT APPLE AND NOT BEOS AND NOT HAIKU AND NOT EMSCRIPTEN)
-   find_library(M_LIBRARY m)
-+  if(NOT M_LIBRARY)
-+    find_library(M_LIBRARY m PATHS ${CMAKE_C_IMPLICIT_LINK_DIRECTORIES} NO_DEFAULT_PATH)
-+    if(M_LIBRARY)
-+      set(M_LIBRARY m)
++  block(SCOPE_FOR VARIABLES)
++    if(VCPKG_CRT_LINKAGE STREQUAL "static")
++      list(PREPEND CMAKE_FIND_LIBRARY_SUFFIXES "${CMAKE_STATIC_LIBRARY_SUFFIX}")
 +    endif()
-+  endif()
-   if(NOT M_LIBRARY)
-     set(M_LIBRARY "")
-   endif()
++    find_library(M_LIBRARY m PATHS ${CMAKE_C_IMPLICIT_LINK_DIRECTORIES})
++  endblock()
+   find_library(M_LIBRARY m)
+   if(M_LIBRARY)
+     set(M_LIBRARY m)
diff --git a/ports/libpng/portfile.cmake b/ports/libpng/portfile.cmake
index 1f09145668..87dce11ec7 100644
--- a/ports/libpng/portfile.cmake
+++ b/ports/libpng/portfile.cmake
@@ -13,7 +13,7 @@ if ("apng" IN_LIST FEATURES)
     vcpkg_download_distfile(LIBPNG_APNG_PATCH_ARCHIVE
         URLS "https://downloads.sourceforge.net/project/libpng-apng/libpng16/${VERSION}/${LIBPNG_APNG_PATCH_NAME}.gz"
         FILENAME "${LIBPNG_APNG_PATCH_NAME}.gz"
-        SHA512 373cc9f0df15f7c77c0a59ddaac22374cfae37174b63a642e68e3a17a6d0bb1015399d771998c7eb6b356b634f157f0009743f4cc659f3b8e480a9533010ef9c
+        SHA512 a724f7de486920cb119818f7172fb589bc2c3c1cc1f81bb5c4da0609ab108ef9ef7406cf689a20bc4e8da69647847f550ed497b3fa99a10539e9a0abf492c053
     )
     set(LIBPNG_APNG_PATCH_PATH "${CURRENT_BUILDTREES_DIR}/src/${LIBPNG_APNG_PATCH_NAME}")
     if (NOT EXISTS "${LIBPNG_APNG_PATCH_PATH}")
@@ -32,7 +32,7 @@ vcpkg_from_github(
     OUT_SOURCE_PATH SOURCE_PATH
     REPO glennrp/libpng
     REF v${VERSION}
-    SHA512 5f36a145c7d41f1c417d5f4e03be0155dae3499d72e67170acaad92c1af418c0bb6bc508e9b4b27ef4206bf0074cbf74978bade3bff28bc291867b8f8c2a38cf
+    SHA512 3bb2a7b73113be42b09c2116e6c6f5a7ddb4e2ab06e0b13e10b7314acdccc4bb624ff602e16140c0484f6cde80efa190296226be3da195c6926819f07c723c12
     HEAD_REF master
     PATCHES
         "${LIBPNG_APNG_PATCH_PATH}"
diff --git a/ports/libpng/vcpkg.json b/ports/libpng/vcpkg.json
index 7661399e25..1502185df3 100644
--- a/ports/libpng/vcpkg.json
+++ b/ports/libpng/vcpkg.json
@@ -1,7 +1,6 @@
 {
   "name": "libpng",
-  "version": "1.6.40",
-  "port-version": 1,
+  "version": "1.6.43",
   "description": "libpng is a library implementing an interface for reading and writing PNG (Portable Network Graphics) format files",
   "homepage": "https://github.com/glennrp/libpng",
   "license": "libpng-2.0",
diff --git a/versions/baseline.json b/versions/baseline.json
index d40896dbd1..0d783b2d6d 100644
--- a/versions/baseline.json
+++ b/versions/baseline.json
@@ -4737,8 +4737,8 @@
       "port-version": 1
     },
     "libpng": {
-      "baseline": "1.6.40",
-      "port-version": 1
+      "baseline": "1.6.43",
+      "port-version": 0
     },
     "libpopt": {
       "baseline": "1.16",
diff --git a/versions/l-/libpng.json b/versions/l-/libpng.json
index b3dbf52a54..c9192d6871 100644
--- a/versions/l-/libpng.json
+++ b/versions/l-/libpng.json
@@ -1,5 +1,10 @@
 {
   "versions": [
+    {
+      "git-tree": "8673cfd41804628ce52c499b8d23c5696104ec47",
+      "version": "1.6.43",
+      "port-version": 0
+    },
     {
       "git-tree": "8b6d2c1150541a94c0ca5b2f060eb21eed4a40b2",
       "version": "1.6.40",