diff --git a/ports/blosc/portfile.cmake b/ports/blosc/portfile.cmake
index 926dc4a63a..42d07f75b3 100644
--- a/ports/blosc/portfile.cmake
+++ b/ports/blosc/portfile.cmake
@@ -2,7 +2,7 @@ vcpkg_from_github(
     OUT_SOURCE_PATH SOURCE_PATH
     REPO Blosc/c-blosc
     REF "v${VERSION}"
-    SHA512 01e6d80e1114d76c4bd1b413778c293d0455879ec38e1e1ec46e8e7eaf2997b47cc2de35bc52cdc4c2c70341b6f87d70626a9a9c24ffc8b7b170d760efa60c07
+    SHA512 f32ac9ca7dd473f32201cdf4b7bb61a89e8bc3e3d16e027d2c6dc1aa838cb47c42dfed6942c9108532b3920ed22a8c662e7451890177c9bbe6ec5b8ab65362b3
     HEAD_REF master
     PATCHES
       0001-fix-CMake-config.patch
diff --git a/ports/blosc/vcpkg.json b/ports/blosc/vcpkg.json
index a6f7af9975..ad5edf9e95 100644
--- a/ports/blosc/vcpkg.json
+++ b/ports/blosc/vcpkg.json
@@ -1,6 +1,6 @@
 {
   "name": "blosc",
-  "version": "1.21.5",
+  "version": "1.21.6",
   "description": "A blocking, shuffling and loss-less compression library that can be faster than `memcpy()`",
   "homepage": "https://github.com/Blosc/c-blosc",
   "license": "BSD-3-Clause",
diff --git a/versions/b-/blosc.json b/versions/b-/blosc.json
index db75f6608d..f7d5720a09 100644
--- a/versions/b-/blosc.json
+++ b/versions/b-/blosc.json
@@ -1,5 +1,10 @@
 {
   "versions": [
+    {
+      "git-tree": "864998aec116af2c008676f9e3be350be747654d",
+      "version": "1.21.6",
+      "port-version": 0
+    },
     {
       "git-tree": "7c0e6152db6058a53ff21fc8037e5c9e685a0fe8",
       "version": "1.21.5",
diff --git a/versions/baseline.json b/versions/baseline.json
index 597534e6a8..ded7185f3a 100644
--- a/versions/baseline.json
+++ b/versions/baseline.json
@@ -705,7 +705,7 @@
       "port-version": 0
     },
     "blosc": {
-      "baseline": "1.21.5",
+      "baseline": "1.21.6",
       "port-version": 0
     },
     "blpapi": {